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Biophysical and Pharmacological Characterization of Energy-Dependent Efflux of Sb in Laboratory-Selected Resistant Strains of Leishmania (Viannia) Subgenus
The growing resistance of leishmaniasis to first-line drugs like antimonials in some regions limits the control of this parasitic disease. The precise mechanisms involved in Leishmania antimony resistance are still subject to debate. The reduction of intracellular Sb(III) accumulation is a common ch...
Autores principales: | dos Reis, Priscila G., do Monte-Neto, Rubens L., Melo, Maria N., Frézard, Frédéric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364148/ https://www.ncbi.nlm.nih.gov/pubmed/28393067 http://dx.doi.org/10.3389/fcell.2017.00024 |
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