Can MRI T(1) be used to detect early changes in 5xFAD Alzheimer’s mouse brain?

OBJECTIVES: In the present study, we have tested whether MRI T(1) relaxation time is a sensitive marker to detect early stages of amyloidosis and gliosis in the young 5xFAD transgenic mouse, a well-established animal model for Alzheimer’s disease. MATERIALS AND METHODS: 5xFAD and wild-type mice were...

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Detalles Bibliográficos
Autores principales: Spencer, Nicholas G., Lovell, David P., Elderfield, Kay, Austen, Brian, Howe, Franklyn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364252/
https://www.ncbi.nlm.nih.gov/pubmed/27785640
http://dx.doi.org/10.1007/s10334-016-0593-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364252/
https://www.ncbi.nlm.nih.gov/pubmed/27785640
http://dx.doi.org/10.1007/s10334-016-0593-9

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