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Can MRI T(1) be used to detect early changes in 5xFAD Alzheimer’s mouse brain?
OBJECTIVES: In the present study, we have tested whether MRI T(1) relaxation time is a sensitive marker to detect early stages of amyloidosis and gliosis in the young 5xFAD transgenic mouse, a well-established animal model for Alzheimer’s disease. MATERIALS AND METHODS: 5xFAD and wild-type mice were...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364252/ https://www.ncbi.nlm.nih.gov/pubmed/27785640 http://dx.doi.org/10.1007/s10334-016-0593-9 |