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Applicability of predictive toxicology methods for monoclonal antibody therapeutics: status Quo and scope

Biopharmaceuticals, monoclonal antibody (mAb)-based therapeutics in particular, have positively impacted millions of lives. MAbs and related therapeutics are highly desirable from a biopharmaceutical perspective as they are highly target specific and well tolerated within the human system. Neverthel...

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Detalles Bibliográficos
Autores principales: Kizhedath, Arathi, Wilkinson, Simon, Glassey, Jarka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364268/
https://www.ncbi.nlm.nih.gov/pubmed/27766364
http://dx.doi.org/10.1007/s00204-016-1876-7