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Salmonella enterica Serovar Typhi Lipopolysaccharide O-Antigen Modification Impact on Serum Resistance and Antibody Recognition

Salmonella enterica serovar Typhi is a human-restricted Gram-negative bacterial pathogen responsible for causing an estimated 27 million cases of typhoid fever annually, leading to 217,000 deaths, and current vaccines do not offer full protection. The O-antigen side chain of the lipopolysaccharide i...

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Detalles Bibliográficos
Autores principales: Kintz, Erica, Heiss, Christian, Black, Ian, Donohue, Nicholas, Brown, Naj, Davies, Mark R., Azadi, Parastoo, Baker, Stephen, Kaye, Paul M., van der Woude, Marjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364305/
https://www.ncbi.nlm.nih.gov/pubmed/28167670
http://dx.doi.org/10.1128/IAI.01021-16