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Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!)

BACKGROUND: rVSV-ZEBOV is a recombinant, replication competent vesicular stomatitis virus-based candidate vaccine expressing a surface glycoprotein of Zaire Ebolavirus. We tested the effect of rVSV-ZEBOV in preventing Ebola virus disease in contacts and contacts of contacts of recently confirmed cas...

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Detalles Bibliográficos
Autores principales: Henao-Restrepo, Ana Maria, Camacho, Anton, Longini, Ira M, Watson, Conall H, Edmunds, W John, Egger, Matthias, Carroll, Miles W, Dean, Natalie E, Diatta, Ibrahima, Doumbia, Moussa, Draguez, Bertrand, Duraffour, Sophie, Enwere, Godwin, Grais, Rebecca, Gunther, Stephan, Gsell, Pierre-Stéphane, Hossmann, Stefanie, Watle, Sara Viksmoen, Kondé, Mandy Kader, Kéïta, Sakoba, Kone, Souleymane, Kuisma, Eewa, Levine, Myron M, Mandal, Sema, Mauget, Thomas, Norheim, Gunnstein, Riveros, Ximena, Soumah, Aboubacar, Trelle, Sven, Vicari, Andrea S, Røttingen, John-Arne, Kieny, Marie-Paule
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364328/
https://www.ncbi.nlm.nih.gov/pubmed/28017403
http://dx.doi.org/10.1016/S0140-6736(16)32621-6