ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with Transcription

We investigated the relationship among ERK signaling, histone modifications, and transcription factor activity, focusing on the ERK-regulated ternary complex factor family of SRF partner proteins. In MEFs, activation of ERK by TPA stimulation induced a common pattern of H3K9acS10ph, H4K16ac, H3K27ac...

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Detalles Bibliográficos
Autores principales: Esnault, Cyril, Gualdrini, Francesco, Horswell, Stuart, Kelly, Gavin, Stewart, Aengus, East, Phil, Matthews, Nik, Treisman, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364370/
https://www.ncbi.nlm.nih.gov/pubmed/28286024
http://dx.doi.org/10.1016/j.molcel.2017.02.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364370/
https://www.ncbi.nlm.nih.gov/pubmed/28286024
http://dx.doi.org/10.1016/j.molcel.2017.02.005

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