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Restoring the oncosuppressor activity of microRNA-34a in glioblastoma using a polyglycerol-based polyplex
Glioblastoma multiforme (GBM) is the most common and aggressive primary neoplasm of the brain. Poor prognosis is mainly attributed to tumor heterogeneity, invasiveness, and drug resistance. microRNA-based therapeutics represent a promising approach due to their ability to inhibit multiple targets. I...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364374/ https://www.ncbi.nlm.nih.gov/pubmed/27262933 http://dx.doi.org/10.1016/j.nano.2016.05.016 |