Cargando…

Unidirectional Transport Mechanism in an ATP Dependent Exporter

[Image: see text] ATP-binding cassette (ABC) transporters use the energy of ATP binding and hydrolysis to move a large variety of compounds across biological membranes. P-glycoprotein, involved in multidrug resistance, is the most investigated eukaryotic family member. Although a large number of bio...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Yanyan, Seelig, Anna, Bernèche, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364450/
https://www.ncbi.nlm.nih.gov/pubmed/28386603
http://dx.doi.org/10.1021/acscentsci.7b00068