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Endogenous opioids regulate moment-to-moment neuronal communication and excitability

Fear and emotional learning are modulated by endogenous opioids but the cellular basis for this is unknown. The intercalated cells (ITCs) gate amygdala output and thus regulate the fear response. Here we find endogenous opioids are released by synaptic stimulation to act via two distinct mechanisms...

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Detalles Bibliográficos
Autores principales: Winters, Bryony L., Gregoriou, Gabrielle C., Kissiwaa, Sarah A., Wells, Oliver A., Medagoda, Danashi I., Hermes, Sam M., Burford, Neil T., Alt, Andrew, Aicher, Sue A., Bagley, Elena E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364458/
https://www.ncbi.nlm.nih.gov/pubmed/28327612
http://dx.doi.org/10.1038/ncomms14611