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Protein interaction evolution from promiscuity to specificity with reduced flexibility in an increasingly complex network

A key question regarding protein evolution is how proteins adapt to the dynamic environment in which they function and how in turn their evolution shapes the protein interaction network. We used extant and resurrected ancestral plant MADS-domain transcription factors to understand how SEPALLATA3, a...

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Detalles Bibliográficos
Autores principales: Alhindi, T., Zhang, Z., Ruelens, P., Coenen, H., Degroote, H., Iraci, N., Geuten, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364480/
https://www.ncbi.nlm.nih.gov/pubmed/28337996
http://dx.doi.org/10.1038/srep44948