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Renin-angiotensin system acting on reactive oxygen species in paraventricular nucleus induces sympathetic activation via AT1R/PKCγ/Rac1 pathway in salt-induced hypertension

Brain renin-angiotensin system (RAS) could regulate oxidative stress in the paraventricular nucleus (PVN) in the development of hypertension. This study was designed to explore the precise mechanisms of RAS acting on reactive oxygen species (ROS) in salt-induced hypertension. Male Wistar rats were a...

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Detalles Bibliográficos
Autores principales: Su, Qing, Huo, Chan-Juan, Li, Hong-Bao, Liu, Kai-Li, Li, Xiang, Yang, Qing, Song, Xin-Ai, Chen, Wen-Sheng, Cui, Wei, Zhu, Guo-Qing, Shi, Xiao-Lian, Liu, Jin-Jun, Kang, Yu-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364504/
https://www.ncbi.nlm.nih.gov/pubmed/28338001
http://dx.doi.org/10.1038/srep43107