جاري التحميل…
Gsα Controls Cortical Bone Quality by Regulating Osteoclast Differentiation via cAMP/PKA and β-Catenin Pathways
Skeletal bone formation and maintenance requires coordinate functions of several cell types, including bone forming osteoblasts and bone resorbing osteoclasts. Gsα, the stimulatory subunit of heterotrimeric G proteins, activates downstream signaling through cAMP and plays important roles in skeletal...
المؤلفون الرئيسيون: | , , , , , , , , |
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التنسيق: | Online مقال نص |
اللغة: | English |
منشور في: |
Nature Publishing Group
2017
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الموضوعات: | |
الوصول للمادة أونلاين: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364530/ https://www.ncbi.nlm.nih.gov/pubmed/28338087 http://dx.doi.org/10.1038/srep45140 |