Gsα Controls Cortical Bone Quality by Regulating Osteoclast Differentiation via cAMP/PKA and β-Catenin Pathways

Skeletal bone formation and maintenance requires coordinate functions of several cell types, including bone forming osteoblasts and bone resorbing osteoclasts. Gsα, the stimulatory subunit of heterotrimeric G proteins, activates downstream signaling through cAMP and plays important roles in skeletal...

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Detalles Bibliográficos
Autores principales: Ramaswamy, Girish, Kim, Hyunsoo, Zhang, Deyu, Lounev, Vitali, Wu, Joy Y., Choi, Yongwon, Kaplan, Frederick S., Pignolo, Robert J., Shore, Eileen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364530/
https://www.ncbi.nlm.nih.gov/pubmed/28338087
http://dx.doi.org/10.1038/srep45140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364530/
https://www.ncbi.nlm.nih.gov/pubmed/28338087
http://dx.doi.org/10.1038/srep45140

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