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Absence of a gestational diabetes phenotype in the LepRdb/+ mouse is independent of control strain, diet, misty allele, or parity

Treatment options for gestational diabetes (GDM) are limited. In order to better understand mechanisms and improve treatments, appropriate animal models of GDM are crucial. Heterozygous db mice (db/+) present with glucose intolerance, insulin resistance, and increased weight gain during, but not pri...

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Detalles Bibliográficos
Autores principales: Plows, Jasmine F., Yu, XinYang, Broadhurst, Ric, Vickers, Mark H., Tong, Chao, Zhang, Hua, Qi, HongBo, Stanley, Joanna L., Baker, Philip N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364537/
https://www.ncbi.nlm.nih.gov/pubmed/28338021
http://dx.doi.org/10.1038/srep45130