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Veratridine produces distinct calcium response profiles in mouse Dorsal Root Ganglia neurons

Nociceptors are a subpopulation of dorsal root ganglia (DRG) neurons that detect noxious stimuli and signal pain. Veratridine (VTD) is a voltage-gated sodium channel (VGSC) modifier that is used as an “agonist” in functional screens for VGSC blockers. However, there is very little information on VTD...

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Detalles Bibliográficos
Autores principales: Mohammed, Zainab A., Doran, Ciara, Grundy, David, Nassar, Mohammed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364547/
https://www.ncbi.nlm.nih.gov/pubmed/28338073
http://dx.doi.org/10.1038/srep45221