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miR-21 enhances cardiac fibrotic remodeling and fibroblast proliferation via CADM1/STAT3 pathway

BACKGROUND: Cardiac fibrosis play a key role in the atrial fibrillation pathogenesis but the underlying potential molecular mechanism is still understood. However, potential mechanisms for miR-21 upregulation and its role in cardiac fibrosis remain unclear. The controls cell proliferation and proces...

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Detalles Bibliográficos
Autores principales: Cao, Wei, Shi, Peng, Ge, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364650/
https://www.ncbi.nlm.nih.gov/pubmed/28335740
http://dx.doi.org/10.1186/s12872-017-0520-7