DHA brain uptake and APOE4 status: a PET study with [1-(11)C]-DHA

BACKGROUND: The apolipoprotein E ɛ4 (APOE4) allele is the strongest genetic risk factor identified for developing Alzheimer’s disease (AD). Among brain lipids, alteration in the ω-3 polyunsaturated fatty acid docosahexaenoic acid (DHA) homeostasis is implicated in AD pathogenesis. APOE4 may influenc...

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Detalles Bibliográficos
Autores principales: Yassine, Hussein N., Croteau, Etienne, Rawat, Varun, Hibbeln, Joseph R., Rapoport, Stanley I., Cunnane, Stephen C., Umhau, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364667/
https://www.ncbi.nlm.nih.gov/pubmed/28335828
http://dx.doi.org/10.1186/s13195-017-0250-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364667/
https://www.ncbi.nlm.nih.gov/pubmed/28335828
http://dx.doi.org/10.1186/s13195-017-0250-1

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