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Sex-determining region Y-box protein 3 induces epithelial-mesenchymal transition in osteosarcoma cells via transcriptional activation of Snail1

BACKGROUND: The transcription factor sex-determining region Y-box protein 3 (SOX3) plays important roles in various types of cancer. However, its expression and function have not yet been elucidated in osteosarcoma (OS). METHODS: The expression levels of SOX3 in OS tissues and OS cell lines were det...

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Detalles Bibliográficos
Autores principales: Qiu, Manle, Chen, Daoyun, Shen, Chaoyong, Shen, Ji, Zhao, Huakun, He, Yaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364714/
https://www.ncbi.nlm.nih.gov/pubmed/28335789
http://dx.doi.org/10.1186/s13046-017-0515-3