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Successful application of large microneedle patches by human volunteers

We describe, for the first time, the design, production and evaluation of large microneedle patches. Such systems, based on 16 individual microneedle arrays (needle height 600 μm), were prepared from aqueous blends of 15% w/w Gantrez(®) S97 and 7.5% w/w poly(ethyleneglycol) 10,000 Da. Ester-based cr...

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Detalles Bibliográficos
Autores principales: Ripolin, Anastasia, Quinn, James, Larrañeta, Eneko, Vicente-Perez, Eva Maria, Barry, Johanne, Donnelly, Ryan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364775/
https://www.ncbi.nlm.nih.gov/pubmed/28216463
http://dx.doi.org/10.1016/j.ijpharm.2017.02.011