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Targeting ROCK2 rather than ROCK1 inhibits Ewing sarcoma malignancy

Understanding the molecular processes characterizing Ewing sarcoma (EWS) cell migration is crucial to highlight novel therapies for patients with disseminated disease. In this study we analyzed the role of ROCK kinases in the regulation of cell migration, growth and differentiation of EWS cells. Ove...

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Detalles Bibliográficos
Autores principales: Pinca, Rosa Simona, Manara, Maria Cristina, Chiadini, Valentina, Picci, Piero, Zucchini, Cinzia, Scotlandi, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364828/
https://www.ncbi.nlm.nih.gov/pubmed/28112365
http://dx.doi.org/10.3892/or.2017.5397