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Safety and toxicology of the intravenous administration of Ang2-siRNA plasmid chitosan magnetic nanoparticles
This aim of the present study was to investigate the safety and toxicology of intravenous administration of angiopoietin-2 (Ang2)-small interfering (si)RNA plasmid-chitosan magnetic nanoparticles (CMNPs). Ang2-CMNPs were constructed and subsequently administered at different doses to mice and rats v...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364838/ https://www.ncbi.nlm.nih.gov/pubmed/28035391 http://dx.doi.org/10.3892/mmr.2016.6090 |