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Inhibiting purinergic P2X7 receptors with the antagonist brilliant blue G is neuroprotective in an intranigral lipopolysaccharide animal model of Parkinson's disease

Parkinson's disease (PD) is a common neurodegenerative disorder, which is characterized by the selective and progressive death of dopaminergic (DA) neurons in the substantia nigra. Increasing evidence suggests that inflammation is important in the degeneration of DA neurons. The purinergic rece...

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Detalles Bibliográficos
Autores principales: Wang, Xin-Hong, Xie, Xin, Luo, Xiao-Guang, Shang, Hong, He, Zhi-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364844/
https://www.ncbi.nlm.nih.gov/pubmed/28035410
http://dx.doi.org/10.3892/mmr.2016.6070