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Inhibiting purinergic P2X7 receptors with the antagonist brilliant blue G is neuroprotective in an intranigral lipopolysaccharide animal model of Parkinson's disease
Parkinson's disease (PD) is a common neurodegenerative disorder, which is characterized by the selective and progressive death of dopaminergic (DA) neurons in the substantia nigra. Increasing evidence suggests that inflammation is important in the degeneration of DA neurons. The purinergic rece...
Autores principales: | Wang, Xin-Hong, Xie, Xin, Luo, Xiao-Guang, Shang, Hong, He, Zhi-Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364844/ https://www.ncbi.nlm.nih.gov/pubmed/28035410 http://dx.doi.org/10.3892/mmr.2016.6070 |
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