Insulin-like growth factor 1 receptor-mediated cell survival in hypoxia depends on the promotion of autophagy via suppression of the PI3K/Akt/mTOR signaling pathway

Hypoxia is widely accepted as a fundamental biological phenomenon, which is strongly associated with tissue damage and cell viability under stress conditions. Insulin-like growth factor-1 (IGF-1) is known to protect tissues from multiple types of damage, and protect cells from apoptosis. Hypoxia is...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Guan, Jing-Zhi, Sun, Yong, Le, Ziyu, Zhang, Ping, Yu, Dong, Liu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364871/
https://www.ncbi.nlm.nih.gov/pubmed/28260056
http://dx.doi.org/10.3892/mmr.2017.6265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364871/
https://www.ncbi.nlm.nih.gov/pubmed/28260056
http://dx.doi.org/10.3892/mmr.2017.6265

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