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Insulin-like growth factor 1 receptor-mediated cell survival in hypoxia depends on the promotion of autophagy via suppression of the PI3K/Akt/mTOR signaling pathway

Hypoxia is widely accepted as a fundamental biological phenomenon, which is strongly associated with tissue damage and cell viability under stress conditions. Insulin-like growth factor-1 (IGF-1) is known to protect tissues from multiple types of damage, and protect cells from apoptosis. Hypoxia is...

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Detalles Bibliográficos
Autores principales:	Liu, Qi, Guan, Jing-Zhi, Sun, Yong, Le, Ziyu, Zhang, Ping, Yu, Dong, Liu, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364871/ https://www.ncbi.nlm.nih.gov/pubmed/28260056 http://dx.doi.org/10.3892/mmr.2017.6265

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