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MicroRNA-34c is regulated by p53 and is involved in sevoflurane-induced apoptosis in the developing rat brain potentially via the mitochondrial pathway

The commonly used inhalation anesthetic, sevoflurane, has been previously demonstrated to induce apoptosis in the developing brain; however, the underlying molecular mechanisms remain largely unknown. MicroRNAs (miRNAs) serve important roles in multiple physiological/pathological processes, such as...

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Detalles Bibliográficos
Autores principales: Zhou, Xue, Xian, Dongfeng, Xia, Jiehua, Tang, Ying, Li, Wenda, Chen, Xiaohui, Zhou, Zhibin, Lu, Dihan, Feng, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364873/
https://www.ncbi.nlm.nih.gov/pubmed/28259954
http://dx.doi.org/10.3892/mmr.2017.6268