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Gremlin-1 suppression increases BMP-2-induced osteogenesis of human mesenchymal stem cells

Previous research focusing on rodent cells and animal models has demonstrated that gremlin-1 antagonizes bone morphogenetic proteins (BMPs) in order to suppress osteogenesis. However, the impact of gremlin-1 on osteogenesis in human bone marrow-derived mesenchymal stem cells (MSCs) remains unknown....

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Detalles Bibliográficos
Autores principales: Hu, Kongzu, Sun, Heyan, Gui, Binjie, Sui, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364878/
https://www.ncbi.nlm.nih.gov/pubmed/28260028
http://dx.doi.org/10.3892/mmr.2017.6253