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Sclareolide enhances gemcitabine-induced cell death through mediating the NICD and Gli1 pathways in gemcitabine-resistant human pancreatic cancer

Pancreatic cancer is a type of cancer, which rapidly develops resistance to chemotherapy. Gemcitabine is the treatment used clinically, however, gemcitabine resistance leads to limited efficacy and patient survival rates of only a few months following diagnosis. The aim of the present study was to i...

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Detalles Bibliográficos
Autores principales: Chen, Sheng, Wang, Ye, Zhang, Wen-Long, Dong, Mao-Sheng, Zhang, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365005/
https://www.ncbi.nlm.nih.gov/pubmed/28259943
http://dx.doi.org/10.3892/mmr.2017.6182