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Reduced expression of SIRT2 in serous ovarian carcinoma promotes cell proliferation through disinhibition of CDK4 expression

The silent information regulator 2 related enzyme 2 (SIRT2) has been reported to have an important role in tumorigenesis. Although two distinct effects of SIRT2 have recently been revealed, which explain opposing expression patterns in different types of cancer, the specific function of SIRT2 in ova...

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Detalles Bibliográficos
Autores principales: Du, Yanhua, Wu, Jun, Zhang, Haiyan, Li, Shaobo, Sun, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365020/
https://www.ncbi.nlm.nih.gov/pubmed/28259910
http://dx.doi.org/10.3892/mmr.2017.6183