γδTCR immunoglobulin constant region domain exchange in human αβTCRs improves TCR pairing without altering TCR gene-modified T cell function

The adoptive genetic transfer of T cell receptors (TCRs) has been shown to be overall feasible and offer clinical potential as a treatment for different types of cancer. However, this promising clinical approach is limited by the serious potential consequence that exogenous TCR mispairing with endog...

Descripción completa

Detalles Bibliográficos
Autores principales: Tao, Changli, Shao, Hongwei, Zhang, Wenfeng, Bo, Huaben, Wu, Fenglin, Shen, Han, Huang, Shulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365024/
https://www.ncbi.nlm.nih.gov/pubmed/28259946
http://dx.doi.org/10.3892/mmr.2017.6206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365024/
https://www.ncbi.nlm.nih.gov/pubmed/28259946
http://dx.doi.org/10.3892/mmr.2017.6206

Ejemplares similares