Zirconocene catalyzed diastereoselective carbometalation of cyclobutenes

The regio- and diastereoselective zirconocene-catalyzed carbomagnesiation of cyclobutenes is herein reported to afford configurationally stable cyclobutylmagnesium species that could subsequently react with a large variety of electrophiles to give polysubstituted cyclobutane species as a single dias...

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Autores principales: Roy, Sudipta Raha, Eijsberg, Hendrik, Bruffaerts, Jeffrey, Marek, Ilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365058/
https://www.ncbi.nlm.nih.gov/pubmed/28451177
http://dx.doi.org/10.1039/c6sc02617f
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author Roy, Sudipta Raha
Eijsberg, Hendrik
Bruffaerts, Jeffrey
Marek, Ilan
author_facet Roy, Sudipta Raha
Eijsberg, Hendrik
Bruffaerts, Jeffrey
Marek, Ilan
author_sort Roy, Sudipta Raha
collection PubMed
description The regio- and diastereoselective zirconocene-catalyzed carbomagnesiation of cyclobutenes is herein reported to afford configurationally stable cyclobutylmagnesium species that could subsequently react with a large variety of electrophiles to give polysubstituted cyclobutane species as a single diastereoisomer.
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spelling pubmed-53650582017-04-27 Zirconocene catalyzed diastereoselective carbometalation of cyclobutenes Roy, Sudipta Raha Eijsberg, Hendrik Bruffaerts, Jeffrey Marek, Ilan Chem Sci Chemistry The regio- and diastereoselective zirconocene-catalyzed carbomagnesiation of cyclobutenes is herein reported to afford configurationally stable cyclobutylmagnesium species that could subsequently react with a large variety of electrophiles to give polysubstituted cyclobutane species as a single diastereoisomer. Royal Society of Chemistry 2017-01-01 2016-08-30 /pmc/articles/PMC5365058/ /pubmed/28451177 http://dx.doi.org/10.1039/c6sc02617f Text en This journal is © The Royal Society of Chemistry 2016 http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 Unported License (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Chemistry
Roy, Sudipta Raha
Eijsberg, Hendrik
Bruffaerts, Jeffrey
Marek, Ilan
Zirconocene catalyzed diastereoselective carbometalation of cyclobutenes
title Zirconocene catalyzed diastereoselective carbometalation of cyclobutenes
title_full Zirconocene catalyzed diastereoselective carbometalation of cyclobutenes
title_fullStr Zirconocene catalyzed diastereoselective carbometalation of cyclobutenes
title_full_unstemmed Zirconocene catalyzed diastereoselective carbometalation of cyclobutenes
title_short Zirconocene catalyzed diastereoselective carbometalation of cyclobutenes
title_sort zirconocene catalyzed diastereoselective carbometalation of cyclobutenes
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365058/
https://www.ncbi.nlm.nih.gov/pubmed/28451177
http://dx.doi.org/10.1039/c6sc02617f
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AT eijsberghendrik zirconocenecatalyzeddiastereoselectivecarbometalationofcyclobutenes
AT bruffaertsjeffrey zirconocenecatalyzeddiastereoselectivecarbometalationofcyclobutenes
AT marekilan zirconocenecatalyzeddiastereoselectivecarbometalationofcyclobutenes

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