Combatting AMR: photoactivatable ruthenium(ii)-isoniazid complex exhibits rapid selective antimycobacterial activity

The novel photoactive ruthenium(ii) complex cis-[Ru(bpy)(2)(INH)(2)][PF(6)](2) (1·2PF(6), INH = isoniazid) was designed to incorporate the anti-tuberculosis drug, isoniazid, that could be released from the Ru(ii) cage by photoactivation with visible light. In aqueous solution, 1 rapidly released two...

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Detalles Bibliográficos
Autores principales: Smith, Nichola A., Zhang, Pingyu, Greenough, Simon E., Horbury, Michael D., Clarkson, Guy J., McFeely, Daniel, Habtemariam, Abraha, Salassa, Luca, Stavros, Vasilios G., Dowson, Christopher G., Sadler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365061/
https://www.ncbi.nlm.nih.gov/pubmed/28451184
http://dx.doi.org/10.1039/c6sc03028a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365061/
https://www.ncbi.nlm.nih.gov/pubmed/28451184
http://dx.doi.org/10.1039/c6sc03028a

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