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Combatting AMR: photoactivatable ruthenium(ii)-isoniazid complex exhibits rapid selective antimycobacterial activity
The novel photoactive ruthenium(ii) complex cis-[Ru(bpy)(2)(INH)(2)][PF(6)](2) (1·2PF(6), INH = isoniazid) was designed to incorporate the anti-tuberculosis drug, isoniazid, that could be released from the Ru(ii) cage by photoactivation with visible light. In aqueous solution, 1 rapidly released two...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365061/ https://www.ncbi.nlm.nih.gov/pubmed/28451184 http://dx.doi.org/10.1039/c6sc03028a |