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STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling
Type I interferons (IFNs) are multifunctional cytokines that regulate immune responses and cellular functions but also can have detrimental effects on human health. A tight regulatory network therefore controls IFN signaling, which in turn interferes with medical interventions. The JAK-STAT signalin...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365074/ https://www.ncbi.nlm.nih.gov/pubmed/28165510 http://dx.doi.org/10.1038/nsmb.3378 |