Cargando…

STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling

Type I interferons (IFNs) are multifunctional cytokines that regulate immune responses and cellular functions but also can have detrimental effects on human health. A tight regulatory network therefore controls IFN signaling, which in turn interferes with medical interventions. The JAK-STAT signalin...

Descripción completa

Detalles Bibliográficos
Autores principales: Arimoto, Kei-ichiro, Löchte, Sara, Stoner, Samuel A., Burkart, Christoph, Zhang, Yue, Miyauchi, Sayuri, Wilmes, Stephan, Fan, Jun-Bao, Heinisch, Jürgen J., Li, Zhi, Yan, Ming, Pellegrini, Sandra, Colland, Frédéric, Piehler, Jacob, Zhang, Dong-Er
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365074/
https://www.ncbi.nlm.nih.gov/pubmed/28165510
http://dx.doi.org/10.1038/nsmb.3378

Ejemplares similares