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In silico search for modifier genes associated with pancreatic and liver disease in Cystic Fibrosis

Cystic Fibrosis is the most common lethal autosomal recessive disorder in the white population, affecting among other organs, the lung, the pancreas and the liver. Whereas Cystic Fibrosis is a monogenic disease, many studies reveal a very complex relationship between genotype and clinical phenotype....

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Detalles Bibliográficos
Autores principales: Trouvé, Pascal, Génin, Emmanuelle, Férec, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365109/
https://www.ncbi.nlm.nih.gov/pubmed/28339466
http://dx.doi.org/10.1371/journal.pone.0173822