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Chronic PARP-1 inhibition reduces carotid vessel remodeling and oxidative damage of the dorsal hippocampus in spontaneously hypertensive rats

Vascular remodeling during chronic hypertension may impair the supply of tissues with oxygen, glucose and other compounds, potentially unleashing deleterious effects. In this study, we used Spontaneously Hypertensive Rats and normotensive Wistar-Kyoto rats with or without pharmacological inhibition...

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Detalles Bibliográficos
Autores principales: Eros, Krisztian, Magyar, Klara, Deres, Laszlo, Skazel, Arpad, Riba, Adam, Vamos, Zoltan, Kalai, Tamas, Gallyas, Ferenc, Sumegi, Balazs, Toth, Kalman, Halmosi, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365133/
https://www.ncbi.nlm.nih.gov/pubmed/28339485
http://dx.doi.org/10.1371/journal.pone.0174401