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Shared regulatory sites are abundant in the human genome and shed light on genome evolution and disease pleiotropy
Large-scale gene expression datasets are providing an increasing understanding of the location of cis-eQTLs in the human genome and their role in disease. However, little is currently known regarding the extent of regulatory site-sharing between genes. This is despite it having potentially wide-rang...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365138/ https://www.ncbi.nlm.nih.gov/pubmed/28282383 http://dx.doi.org/10.1371/journal.pgen.1006673 |