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Metformin prevents hormonal and metabolic disturbances and 1,2-dimethylhydrazine-induced colon carcinogenesis in non-diabetic rats

Effects of two doses of the anti-diabetic drug, metformin (MF), on hormonal and metabolic levels of serum of non-diabetic male Wistar rats with 1,2-dimethylhydrazine (DMH)-induced colon tumor adenocarcinomas were studied. Carcinogenesis in the animals was also observed. Rats with DMH-induced colon a...

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Detalles Bibliográficos
Autores principales: Bekusova, Viktoria V., Patsanovskii, Vasily M., Nozdrachev, Alexander D., Trashkov, Alexandr P., Artemenko, Margarita R., Anisimov, Vladimir N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365186/
https://www.ncbi.nlm.nih.gov/pubmed/28443209
http://dx.doi.org/10.20892/j.issn.2095-3941.2016.0088