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Bottlenecks in the development of topical analgesics: molecule, formulation, dose-finding, and phase III design
Topical analgesics can be defined as topical formulations containing analgesics or co-analgesics. Since 2000, interest in such formulations has been on the rise. There are, however, four critical issues in the research and development phases of topical analgesics: 1) The selection of the active phar...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365321/ https://www.ncbi.nlm.nih.gov/pubmed/28360532 http://dx.doi.org/10.2147/JPR.S131434 |