Pharmacokinetics of the Novel Echinocandin CD101 in Multiple Animal Species

CD101 is a novel semisynthetic echinocandin with antifungal activity against Candida and Aspergillus spp. The pharmacokinetics (PK) of CD101 administered intravenously to mice, rats, dogs, cynomolgus monkeys, and chimpanzees are presented. CD101 consistently exhibited very low clearance, a modest vo...

Descripción completa

Detalles Bibliográficos
Autores principales: Ong, Voon, James, Kenneth D., Smith, Steven, Krishnan, B. Radha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365648/
https://www.ncbi.nlm.nih.gov/pubmed/28137817
http://dx.doi.org/10.1128/AAC.01626-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365648/
https://www.ncbi.nlm.nih.gov/pubmed/28137817
http://dx.doi.org/10.1128/AAC.01626-16

Ejemplares similares