Cyclic Boronates Inhibit All Classes of β-Lactamases

β-Lactamase-mediated resistance is a growing threat to the continued use of β-lactam antibiotics. The use of the β-lactam-based serine-β-lactamase (SBL) inhibitors clavulanic acid, sulbactam, and tazobactam and, more recently, the non-β-lactam inhibitor avibactam has extended the utility of β-lactam...

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Detalles Bibliográficos
Autores principales: Cahill, Samuel T., Cain, Ricky, Wang, David Y., Lohans, Christopher T., Wareham, David W., Oswin, Henry P., Mohammed, Jabril, Spencer, James, Fishwick, Colin W. G., McDonough, Michael A., Schofield, Christopher J., Brem, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365654/
https://www.ncbi.nlm.nih.gov/pubmed/28115348
http://dx.doi.org/10.1128/AAC.02260-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365654/
https://www.ncbi.nlm.nih.gov/pubmed/28115348
http://dx.doi.org/10.1128/AAC.02260-16

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