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Complex multi-enhancer contacts captured by Genome Architecture Mapping (GAM)

The organization of the genome in the nucleus and the interactions of genes with their regulatory elements are key features of transcriptional control and their disruption can cause disease. We developed a novel genome-wide method, Genome Architecture Mapping (GAM), for measuring chromatin contacts,...

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Detalles Bibliográficos
Autores principales: Beagrie, Robert A., Scialdone, Antonio, Schueler, Markus, Kraemer, Dorothee C.A., Chotalia, Mita, Xie, Sheila Q., Barbieri, Mariano, de Santiago, Inês, Lavitas, Liron-Mark, Branco, Miguel R., Fraser, James, Dostie, Josée, Game, Laurence, Dillon, Niall, Edwards, Paul A.W., Nicodemi, Mario, Pombo, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366070/
https://www.ncbi.nlm.nih.gov/pubmed/28273065
http://dx.doi.org/10.1038/nature21411