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Renoprotective Effects of Aldose Reductase Inhibitor Epalrestat against High Glucose-Induced Cellular Injury

Diabetic nephropathy (DN) is the leading cause of end stage renal disease worldwide. Increased glucose flux into the aldose reductase (AR) pathway during diabetes was reported to exert deleterious effects on the kidney. The objective of this study was to investigate the renoprotective effects of AR...

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Detalles Bibliográficos
Autores principales: El Gamal, Heba, Eid, Ali Hussein, Munusamy, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366186/
https://www.ncbi.nlm.nih.gov/pubmed/28386557
http://dx.doi.org/10.1155/2017/5903105