Pathogenic Roles of Glutamic Acid Decarboxylase 65 Autoantibodies in Cerebellar Ataxias

Reports suggesting a pathogenic role of autoantibodies directed against glutamic acid decarboxylase 65 (GAD65Abs) in cerebellar ataxias (CAs) are reviewed, and debatable issues such as internalization of antibodies by neurons and roles of epitopes are discussed. GAD65 is one of two enzymes that cata...

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Detalles Bibliográficos
Autores principales: Mitoma, Hiroshi, Manto, Mario, Hampe, Christiane S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366212/
https://www.ncbi.nlm.nih.gov/pubmed/28386570
http://dx.doi.org/10.1155/2017/2913297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366212/
https://www.ncbi.nlm.nih.gov/pubmed/28386570
http://dx.doi.org/10.1155/2017/2913297

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