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CANCER-ASSOCIATED FIBROBLAST EXOSOMES REGULATE SURVIVAL AND PROLIFERATION OF PANCREATIC CANCER CELLS

Cancer associated fibroblasts (CAFs) comprise the majority of the tumor bulk of pancreatic adenocarcinomas (PDACs). Current efforts to eradicate these tumors focus predominantly on targeting the proliferation of rapidly growing cancer epithelial cells. We know that this is largely ineffective with r...

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Detalles Bibliográficos
Autores principales: Richards, Katherine E., Zeleniak, Ann E., Fishel, Melissa L., Wu, Junmin, Littlepage, Laurie E., Hill, Reginald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366272/
https://www.ncbi.nlm.nih.gov/pubmed/27669441
http://dx.doi.org/10.1038/onc.2016.353