Electron Microscopy Structural Insights into CPAP Oligomeric Behavior: A Plausible Assembly Process of a Supramolecular Scaffold of the Centrosome

Centrosomal P4.1-associated protein (CPAP) is a cell cycle regulated protein fundamental for centrosome assembly and centriole elongation. In humans, the region between residues 897–1338 of CPAP mediates interactions with other proteins and includes a homodimerization domain. CPAP mutations cause pr...

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Detalles Bibliográficos
Autores principales: Alvarez-Cabrera, Ana L., Delgado, Sandra, Gil-Carton, David, Mortuza, Gulnahar B., Montoya, Guillermo, Sorzano, Carlos O. S., Tang, Tang K., Carazo, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366329/
https://www.ncbi.nlm.nih.gov/pubmed/28396859
http://dx.doi.org/10.3389/fmolb.2017.00017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366329/
https://www.ncbi.nlm.nih.gov/pubmed/28396859
http://dx.doi.org/10.3389/fmolb.2017.00017

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