The KIF1A homolog Unc-104 is important for spontaneous release, postsynaptic density maturation and perisynaptic scaffold organization

The kinesin-3 family member KIF1A has been shown to be important for experience dependent neuroplasticity. In Drosophila, amorphic mutations in the KIF1A homolog unc-104 disrupt the formation of mature boutons. Disease associated KIF1A mutations have been associated with motor and sensory dysfunctio...

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Detalles Bibliográficos
Autores principales: Zhang, Yao V., Hannan, Shabab B., Kern, Jeannine V., Stanchev, Doychin T., Koç, Baran, Jahn, Thomas R., Rasse, Tobias M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366810/
https://www.ncbi.nlm.nih.gov/pubmed/28344334
http://dx.doi.org/10.1038/srep38172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366810/
https://www.ncbi.nlm.nih.gov/pubmed/28344334
http://dx.doi.org/10.1038/srep38172

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