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Acute and chronic mitochondrial respiratory chain deficiency differentially regulate lysosomal biogenesis

Mitochondria are key cellular signaling platforms, affecting fundamental processes such as cell proliferation, differentiation and death. However, it remains unclear how mitochondrial signaling affects other organelles, particularly lysosomes. Here, we demonstrate that mitochondrial respiratory chai...

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Detalles Bibliográficos
Autores principales: Fernández-Mosquera, Lorena, Diogo, Cátia V., Yambire, King Faisal, Santos, Gabriela L., Luna Sánchez, Marta, Bénit, Paule, Rustin, Pierre, Lopez, Luis Carlos, Milosevic, Ira, Raimundo, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366864/
https://www.ncbi.nlm.nih.gov/pubmed/28345620
http://dx.doi.org/10.1038/srep45076